Wilms tumour
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine
Link
https://www.nature.com/articles/s41572-021-00308-8.pdf
Reference236 articles.
1. Pastore, G. et al. Malignant renal tumours incidence and survival in European children (1978–1997): report from the Automated Childhood Cancer Information System project. Eur. J. Cancer 42, 2103–2114 (2006).
2. Nakata, K., Colombet, M., Stiller, C. A., Pritchard-Jones, K. & Steliarova-Foucher, E. Incidence of childhood renal tumours: an international population-based study. Int. J. Cancer 147, 3313–3327 (2020).
3. Treger, T. D., Chowdhury, T., Pritchard-Jones, K. & Behjati, S. The genetic changes of Wilms tumour. Nat. Rev. Nephrol. 15, 240–251 (2019).
4. Young, M. D. et al. Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors. Science 361, 594–599 (2018).
5. Coorens, T. H. H. et al. Embryonal precursors of Wilms tumor. Science 366, 1247–1251 (2019). Comprehensive phylogenetic analysis that found premalignant clonal expansions (defined by somatic mutations shared between tumour and normal tissues but absent from blood cells) in morphologically normal kidney that preceded WT development. Clonal expansions evolving before the divergence of left and right kidney primordia may explain a proportion of bilateral WT cases.
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