Activity-based protein profiling for biochemical pathway discovery in cancer-Reference-Cited by-同舟云学术

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Activity-based protein profiling for biochemical pathway discovery in cancer

Published:2010-08-12 Issue:9 Volume:10 Page:630-638
ISSN:1474-175X
Container-title:Nature Reviews Cancer
language:en
Short-container-title:Nat Rev Cancer

Author:

Nomura Daniel K.,Dix Melissa M.,Cravatt Benjamin F.

Publisher

Springer Science and Business Media LLC

Subject

General Earth and Planetary Sciences,General Environmental Science

Link

http://www.nature.com/articles/nrc2901.pdf

Reference100 articles.

1. Deberardinis, R. J., Lum, J. J., Hatzivassiliou, G. & Thompson, C. B. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell. Metab. 7, 11–20 (2008).

2. Vander Heiden, M. G., Cantley, L. C. & Thompson, C. B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324, 1029–1033 (2009).

3. Warburg, O. On respiratory impairment in cancer cells. Science 124, 269–270 (1956).

4. Warburg, O. On the origin of cancer cells. Science 123, 309–314 (1956). A seminal paper describing how cancer cells primarily depend on glycolysis for energy, showing that cancer cells have a fundamentally altered metabolism compared with normal cells.

5. Christofk, H. R. et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 452, 230–233 (2008). This paper shows that the M2 isoform of pyruvate kinase is responsible for the Warburg effect.

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