Proteome-wide Ligand and Target Discovery by Using Strain-Enabled Cyclopropane Electrophiles

Author:

Liu Yue123,Yu Zhongtang123,Li Peishan123,Yang Tao123,Ding Ke123ORCID,Zhang Zhi-Min123,Tan Yi123ORCID,Li Zhengqiu1243ORCID

Affiliation:

1. State Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, China

2. International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development (MOE), Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, China

3. School of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, China

4. MOE Key Laboratory of Tumor Molecular Biology, Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, China

Funder

Guangdong Science and Technology Department

Basic and Applied Basic Research Foundation of Guangdong Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

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