Review article: esomeprazole − the first proton pump inhibitor to be developed as an isomer

Author:

Kendall M. J.

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

Reference7 articles.

1. Chiral switch, a successful way for developing drugs: example of esomeprazole;Creutzfeldt;Z Gastroenterol,2000

2. Pharmacokinetic studies with esomeprazole, the (S)-isomer of omeprazole;Andersson;Clin Pharmacokinet,2001

3. Pharmacokinetics (PK) and effect on pentagastrin stimulated peak acid output (PAO) of omeprazole (O) and its 2 optical isomers, S-omeprazole/esomeprazole (E) and R-omeprazole (R-O);Andersson;Gastroenterology,2000

4. Stereoselective metabolism of omeprazole by human cytochrome P450 enzymes;Äbelö;Drug Metab Dispos,2000

5. Johnson DA Benjamin SB Vakil NB et al. Esomeprazole once daily for 6 months is effective therapy for maintaining healed erosive esophagitis and for controlling gastroesophageal reflux disease symptoms: a randomized, double-blind, placebo-controlled study of efficacy and safety Am J Gastroenterol 2001 96 27 34

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