Expanding the toolbox of Baeyer–Villiger and flavin monooxygenase biocatalysts for the enantiodivergent green synthesis of sulfoxides-Reference-Cited by-同舟云学术

Expanding the toolbox of Baeyer–Villiger and flavin monooxygenase biocatalysts for the enantiodivergent green synthesis of sulfoxides

Published:2024 Issue:15 Volume:26 Page:8685-8693
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Wu Jingyue¹^ORCID,Anselmi Silvia¹^ORCID,Carvalho Alexandra T. P.²^ORCID,Caswell Jill²,Quinn Derek J.²,Moody Thomas S.²³,Castagnolo Daniele¹^ORCID

Affiliation:

1. Department of Chemistry, University College London, 20 Gordon Street, WC1H 0AJ, London, UK

2. Department of Biocatalysis & Isotope Chemistry, Almac, 20 Seagoe Industrial Estate, Craigavon, BT63 5QD, UK

3. Arran Chemical Company Limited, Unit 1 Monksland Industrial Estate, Athlone, Co. Roscommon, Ireland

Abstract

Two new monooxygenase biocatalysts, BVMO145 and FMO401 from Almac library, catalyse the enantiodivergent oxidation of sulfides bearing N-heterocyclic substituents into sulfoxides under mild and green conditions.

Funder

Biotechnology and Biological Sciences Research Council

University Postgraduate Programme

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/GC/D4GC02657H

Reference38 articles.

1. Chiral sulfoxides: advances in asymmetric synthesis and problems with the accurate determination of the stereochemical outcome

2. R-Modafinil (Armodafinil): A Unique Dopamine Uptake Inhibitor and Potential Medication for Psychostimulant Abuse

3. Review article: esomeprazole − the first proton pump inhibitor to be developed as an isomer

4. T.Jia , M.Wang and J.Liao , in Sulfur Chemistry , ed. X. Jiang , Springer International Publishing , Cham , 2019 , pp. 399–427

5. Chiral Sulfur Ligands for Asymmetric Catalysis