Influence of CYP2B6 Pharmacogenetics on Stereoselective Inhibition and Induction of Bupropion Metabolism by Efavirenz in Healthy Volunteers
Author:
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Subject
Pharmacology,Molecular Medicine
Reference61 articles.
1. Bamfo NO Lu JBL Desta Z (2022) Stereoselective metabolism of bupropion to active metabolites in cellular fractions of human liver and intestine. Drug Metab Dispos DOI: 10.1124/dmd.122.000867 [published ahead of print].
2. Glucuronidation of the Antiretroviral Drug Efavirenz by UGT2B7 and an in Vitro Investigation of Drug-Drug Interaction with Zidovudine
3. Influence of CYP2B6 genetic variants on plasma and urine concentrations of bupropion and metabolites at steady state
4. Variants in the CYP2B6 3'UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs;Burgess;Clin Pharmacol Ther,2017
5. Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers
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1. Pharmacogenetic Influence on Stereoselective Steady-State Disposition of Bupropion;Drug Metabolism and Disposition;2024-03-11
2. Expression of CYP2B6 Enzyme in Human Liver Tissue of HIV and HCV Patients;Medicina;2023-06-27
3. In vitro Assessment of the Effects of Silybin on CYP2B6-mediated Metabolism;Planta Medica;2023-05-26
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