Glucuronidation of the Antiretroviral Drug Efavirenz by UGT2B7 and an in Vitro Investigation of Drug-Drug Interaction with Zidovudine-Reference-Cited by-同舟云学术

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Glucuronidation of the Antiretroviral Drug Efavirenz by UGT2B7 and an in Vitro Investigation of Drug-Drug Interaction with Zidovudine

Published:2009-06-01 Issue:9 Volume:37 Page:1793-1796
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Bélanger Anne-Sophie,Caron Patrick,Harvey Mario,Zimmerman Peter A.,Mehlotra Rajeev K.,Guillemette Chantal

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference23 articles.

1. Pharmacogenetics-Based Population Pharmacokinetic Analysis of Efavirenz in HIV-1-Infected Individuals

2. In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function

3. A novel functional polymorphism in the uridine diphosphate–glucuronosyltransferase 2B7 promoter with significant impact on promoter activity

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