Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor-Reference-Cited by-同舟云学术

Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor

Published:2014-03-18 Issue:6 Volume:42 Page:974-982
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Shin Beom Soo,Yoo Sun Dong,Kim Tae Hwan,Bulitta Jurgen B.,Landersdorfer Cornelia B.,Shin Jeong Cheol,Choi Jin Ho,Weon Kwon-Yeon,Joo Sang Hoon,Shin Soyoung

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference43 articles.

1. Apicidin, a histone deaceylase inhibitor, induces both apoptosis and autophagy in human oral squamous carcinoma cells

2. Anti-tumor effect of apicidin on Ishikawa human endometrial cancer cells both in vitro and in vivo by blocking histone deacetylase 3 and 4;Ahn;Int J Oncol,2010

3. Histone deacetylase inhibitor, apicidin, inhibits human ovarian cancer cell migration via class II histone deacetylase 4 silencing

4. Pharmacokinetics of Amitriptyline and One of Its Metabolites, Nortriptyline, in Rats: Little Contribution of Considerable Hepatic First-Pass Effect to Low Bioavailability of Amitriptyline Due to Great Intestinal First-Pass Effect

5. Current methodologies used for evaluation of intestinal permeability and absorption

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