Pharmacokinetics of Amitriptyline and One of Its Metabolites, Nortriptyline, in Rats: Little Contribution of Considerable Hepatic First-Pass Effect to Low Bioavailability of Amitriptyline Due to Great Intestinal First-Pass Effect-Reference-Cited by-同舟云学术

Pharmacokinetics of Amitriptyline and One of Its Metabolites, Nortriptyline, in Rats: Little Contribution of Considerable Hepatic First-Pass Effect to Low Bioavailability of Amitriptyline Due to Great Intestinal First-Pass Effect

Published:2009-04 Issue:4 Volume:98 Page:1587-1601
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Bae Soo K.,Yang Kyung H.,Aryal Dipendra K.,Kim Yoon G.,Lee Myung G.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference27 articles.

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4. Amitriptyline pharmacokinetics;Burch;A. cross study with single doses of amitriptyline and nortriptyline. Psychopharmacology,1981

5. The demethylation of amitriptyline administered by oral and intramuscular routes;Burch;Psychopharmacology,1983

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