Impact of Plasma Protein Binding in Drug Clearance Prediction: A Data Base Analysis of Published Studies and Implications for In Vitro-In Vivo Extrapolation
Author:
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Subject
Pharmaceutical Science,Pharmacology
Reference35 articles.
1. Avdeef A (2012) Octanol water-partitioning, in Absorption and Drug Development pp 174–219, John Wiley & Sons, Inc., Hoboken, NJ.
2. Prediction of in vivo hepatic clearance from in vitro data using cryopreserved human hepatocytes
3. Comparison of clearance predictions using primary cultures and suspensions of human hepatocytes
4. Prediction of hepatic clearance using cryopreserved human hepatocytes: a comparison of serum and serum-free incubations
5. Impact of serum on clearance predictions obtained from suspensions and primary cultures of rat hepatocytes
Cited by 29 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Introducing the Dynamic Well-Stirred Model for Predicting Hepatic Clearance and Extraction Ratio;Journal of Pharmaceutical Sciences;2024-01
2. Mechanistic Static Model based Prediction of Transporter Substrate Drug-Drug Interactions Utilizing Atorvastatin and Rifampicin;Pharmaceutical Research;2023-10-11
3. Mechanistic Static Model based Prediction of Transporter Substrate Drug-Drug Interactions Utilizing Atorvastatin and Rifampicin;PHARM RES-DORDR;2023
4. An artificial intelligence-assisted physiologically-based pharmacokinetic model to predict nanoparticle delivery to tumors in mice;Journal of Controlled Release;2023-09
5. Central and peripheral tau retention modulated by an anti-tau antibody;2023-08-21
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3