Prediction of in vivo hepatic clearance from in vitro data using cryopreserved human hepatocytes
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1080/0049825031000076177
Reference11 articles.
1. ANON. 1994, TDx Assays Manual (Abbott Park: Abbott Laboratories).
2. The Use of In Vitro Methods to Predict In Vivo Pharmacokinetics and Drug Interactions
3. Present and future in vitro approaches for drug metabolism
4. Release of Enzymes by Ricin from Macrophages and Chinese Hamster Ovary Cells in Culture
Cited by 40 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Does Addition of Protein to Hepatocyte or Microsomal In Vitro Incubations Provide a Useful Improvement in In Vitro-In Vivo Extrapolation Predictability?;Drug Metabolism and Disposition;2022-01-27
2. Impact of Plasma Protein Binding in Drug Clearance Prediction: A Data Base Analysis of Published Studies and Implications for In Vitro-In Vivo Extrapolation;Drug Metabolism and Disposition;2020-12-18
3. In vitro and in vivo methods to assess pharmacokinetic drug– drug interactions in drug discovery and development;Biopharmaceutics & Drug Disposition;2020-01-07
4. Metabolic stability and its role in the discovery of new chemical entities;Acta Pharmaceutica;2019-06-26
5. Improved Human Pharmacokinetic Prediction of Hepatically Metabolized Drugs With Species-Specific Systemic Clearance;Journal of Pharmaceutical Sciences;2018-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3