Role of Phosphatidylinositol 3-Kinase/AKT as a Survival Pathway against CYP2E1-Dependent Toxicity
Author:
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Subject
Pharmacology,Molecular Medicine
Reference39 articles.
1. Regulation of Choline Deficiency Apoptosis by Epidermal Growth Factor in CWSV-1 Rat Hepatocytes
2. Anti-apoptotic effect of insulin on normal hepatocytes in vitro and in vivo
3. The Phosphoinositide 3-Kinase Pathway
4. Role of Calcium and Calcium-activated Proteases in CYP2E1-dependent Toxicity in HEPG2 Cells
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1. Cyp2e1 knockdown attenuates high glucose-induced apoptosis and oxidative stress of cardiomyocytes by activating PI3K/Akt signaling;Acta Diabetologica;2023-05-17
2. The orphan nuclear receptor Nurr1 agonist amodiaquine mediates neuroprotective effects in 6-OHDA Parkinson’s disease animal model by enhancing the phosphorylation of P38 mitogen-activated kinase but not PI3K/AKT signaling pathway;Metabolic Brain Disease;2021-01-28
3. Role of GSK-3β in Regulation of Canonical Wnt/β-catenin Signaling and PI3-K/Akt Oncogenic Pathway in Colon Cancer;Cancer Investigation;2017-07-18
4. Effect of BI-1 on insulin resistance through regulation of CYP2E1;Scientific Reports;2016-08-31
5. The Akt inhibitor MK-2206 enhances the cytotoxicity of paclitaxel (Taxol) and cisplatin in ovarian cancer cells;Naunyn-Schmiedeberg's Archives of Pharmacology;2014-08-28
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