The Akt inhibitor MK-2206 enhances the cytotoxicity of paclitaxel (Taxol) and cisplatin in ovarian cancer cells-Reference-Cited by-同舟云学术

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The Akt inhibitor MK-2206 enhances the cytotoxicity of paclitaxel (Taxol) and cisplatin in ovarian cancer cells

Published:2014-08-28 Issue:1 Volume:388 Page:19-31
ISSN:0028-1298
Container-title:Naunyn-Schmiedeberg's Archives of Pharmacology
language:en
Short-container-title:Naunyn-Schmiedeberg's Arch Pharmacol

Author:

Lin Ying-Hsi,Chen Bert Yu-Hung,Lai Wei-Ting,Wu Shao-Fu,Guh Jih-Hwa,Cheng Ann-Lii,Hsu Lih-Ching

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00210-014-1032-y.pdf

Reference26 articles.

1. Agarwal R, Kaye SB (2003) Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat Rev Cancer 3:502–516. doi: 10.1038/nrc1123

2. Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P, Hemmings BA (1996) Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J 15:6541–6551

3. Berkenblit A, Cannistra SA (2005) Advances in the management of epithelial ovarian cancer. J Reprod Med 50:426–438

4. Caro AA, Cederbaum AI (2006) Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity. J Pharmacol Exp Ther 318:360–372. doi: 10.1124/jpet.106.102921

5. Chen H, Ma Z, Vanderwaal RP, Feng Z, Gonzalez-Suarez I, Wang S, Zhang J, Roti Roti JL, Gonzalo S, Zhang J (2011) The mTOR inhibitor rapamycin suppresses DNA double-strand break repair. Radiat Res 175:214–224

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2. An Update on Physiopathological Roles of Akt in the ReprodAKTive Mammalian Ovary;Life;2024-06-02

3. Paclitaxel mediates the PI3K/AKT/mTOR pathway to reduce proliferation of FLT3‑ITD⁺ AML cells and promote apoptosis;Experimental and Therapeutic Medicine;2024-02-23

4. Dual regulation of Akt and glutathione caused by isoalantolactone effectively triggers human ovarian cancer cell apoptosis;Acta Biochimica et Biophysica Sinica;2023-02-01

5. The multifaced role and therapeutic regulation of autophagy in ovarian cancer;Clinical and Translational Oncology;2022-12-19

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