Efavirenz Primary and Secondary Metabolism In Vitro and In Vivo: Identification of Novel Metabolic Pathways and Cytochrome P450 2A6 as the Principal Catalyst of Efavirenz 7-Hydroxylation-Reference-Cited by-同舟云学术

Efavirenz Primary and Secondary Metabolism In Vitro and In Vivo: Identification of Novel Metabolic Pathways and Cytochrome P450 2A6 as the Principal Catalyst of Efavirenz 7-Hydroxylation

Published:2010-03-24 Issue:7 Volume:38 Page:1218-1229
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Ogburn Evan T.,Jones David R.,Masters Andrea R.,Xu Cong,Guo Yingying,Desta Zeruesenay

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference39 articles.

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4. Bristol-Myers Squibb Company (2009) Package insert of efavirenz (Sustiva) at http://packageinserts.bms.com/pi/pi_sustiva.pdf (updated September 2009), New York.

5. Population pharmacokinetics and effects of efavirenz in patients with human immunodeficiency virus infection

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