Arbaclofen Placarbil, a Novel R-Baclofen Prodrug: Improved Absorption, Distribution, Metabolism, and Elimination Properties Compared with R-Baclofen-Reference-Cited by-同舟云学术

Arbaclofen Placarbil, a Novel R-Baclofen Prodrug: Improved Absorption, Distribution, Metabolism, and Elimination Properties Compared with R-Baclofen

Published:2009-06-05 Issue:3 Volume:330 Page:911-921
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Lal Ritu,Sukbuntherng Juthamas,Tai Ezra H. L.,Upadhyay Shubhra,Yao Fenmei,Warren Mark S.,Luo Wendy,Bu Lin,Nguyen Son,Zamora Jeanelle,Peng Ge,Dias Tracy,Bao Ying,Ludwikow Maria,Phan Thu,Scheuerman Randall A.,Yan Hui,Gao Mark,Wu Quincey Q.,Annamalai Thamil,Raillard Stephen P.,Koller Kerry,Gallop Mark A.,Cundy Kenneth C.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference23 articles.

1. Novartis (1977) Lioresal® NDA 17-851 and Summary Basis of Approval, Novartis, Basel, Switzerland.

2. XP13512 [(±)-1-([(α-Isobutanoyloxyethoxy)carbonyl] aminomethyl)-1-cyclohexane Acetic Acid], A Novel Gabapentin Prodrug: I. Design, Synthesis, Enzymatic Conversion to Gabapentin, and Transport by Intestinal Solute Transporters

3. Baclofen for the Treatment of Acute Low-Back Syndrome

4. Molecular Features, Regulation, and Function of Monocarboxylate Transporters: Implications for Drug Delivery

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