Mechanistic Insight from In Silico Pharmacokinetic Experiments: Roles of P-glycoprotein, Cyp3A4 Enzymes, and Microenvironments

Author:

Lam Tai Ning,Hunt C. Anthony

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference38 articles.

1. Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities;Dantzig;J Pharmacol Exp Ther,1999

2. CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavirin vitro

3. Executable cell biology

4. Essential operating principles for tumor spheroid growth

5. Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism;Fitzsimmons;Drug Metab Dispos,1997

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