Exploration of 2-((Pyridin-4-ylmethyl)amino)nicotinamide Derivatives as Potent Reversal Agents against P-Glycoprotein-Mediated Multidrug Resistance-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Exploration of 2-((Pyridin-4-ylmethyl)amino)nicotinamide Derivatives as Potent Reversal Agents against P-Glycoprotein-Mediated Multidrug Resistance

Published:2017-03-24 Issue:7 Volume:60 Page:2930-2943
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Qiu Qianqian¹,Shi Wei¹,Li Zheng¹,Zhang Bo¹,Pan Miaobo¹,Cui Jian¹,Dai Yuxuan¹,Huang Wenlong¹²,Qian Hai¹²^ORCID

Affiliation:

1. Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, P. R. China

2. Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, Nanjing 210009, P. R. China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01879

Reference55 articles.

1. Mechanisms of Cancer Drug Resistance

2. Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

3. Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans

4. Understanding polyspecificity within the substrate-binding cavity of the human multidrug resistance P-glycoprotein

5. Multidrug Resistance Reversal Agent, NSC77037, Identified with a Cell-Based Screening Assay

Cited by 36 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, synthesis, and bioactivity evaluation of novel indole-selenide derivatives as P-glycoprotein inhibitors against multi-drug resistance in MCF-7/ADR cell;European Journal of Medicinal Chemistry;2024-03

2. Designed, Synthesis, In Vitro and Computational Analyses of Anticancer Nicotinamide Derivatives;Indian Journal of Chemistry;2024-02-21

3. Imidazo[1,2-a]Pyridine Derivatives as Novel Dual-Target Inhibitors of ABCB1 and ABCG2 for Reversing Multidrug Resistance;Journal of Medicinal Chemistry;2023-02-13

4. Design, synthesis and biological evaluation of novel phenylfuran-bisamide derivatives as P-glycoprotein inhibitors against multidrug resistance in MCF-7/ADR cell;European Journal of Medicinal Chemistry;2023-02

5. In Silico Exploration and Biological Evaluation of Bispecific Peptides Derived from Anti-HER2 Antibodies and Peptide–Camptothecin Conjugates for HER2-Positive Breast Cancer;Journal of Medicinal Chemistry;2022-11-09

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3