<i>In Silico</i> Exploration and Biological Evaluation of Bispecific Peptides Derived from Anti-HER2 Antibodies and Peptide–Camptothecin Conjugates for HER2-Positive Breast Cancer-Reference-Cited by-同舟云学术

In Silico Exploration and Biological Evaluation of Bispecific Peptides Derived from Anti-HER2 Antibodies and Peptide–Camptothecin Conjugates for HER2-Positive Breast Cancer

Published:2022-11-09 Issue:22 Volume:65 Page:15123-15139
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhou Jiaqi¹,Bian Xiaojian¹,Kan Zigui²,Cai Zilong¹,Jiang Yuxuan¹,Wang Zike¹,Li Yuanyuan¹,Shi Wei¹,Qian Hai¹³^ORCID

Affiliation:

1. Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, PR China

2. School of Science, China Pharmaceutical University, Nanjing 210009, PR China

3. Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, Nanjing 210009, PR China

Funder

China Postdoctoral Science Foundation

Government of Jiangsu Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00968

Reference23 articles.

1. Resistance to Antibody–Drug Conjugates

2. Targeted drug delivery for cancer therapy: the other side of antibodies

3. Peptide-Drug Conjugate: A Novel Drug Design Approach

4. The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis

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