Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P1) Employing Ligand-Based Drug Design
Author:
Affiliation:
1. Research and Development, Bristol-Myers Squibb Company, P.O. Box 4000, Princeton, New Jersey 08543-4000, United States
2. BMS Biocon Research Center, Bangalore 560099, India
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01099
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1. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
2. Investigating the molecular mechanisms through which FTY720-P causes persistent S1P1receptor internalization
3. Mechanism of Action of Oral Fingolimod (FTY720) in Multiple Sclerosis
4. Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists
5. The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors
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