Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis-Reference-Cited by-同舟云学术

Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis

Published:2022-01-25 Issue:4 Volume:65 Page:3539-3562
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Park Sun Jun¹²³,Yeon Seul Ki¹,Kim Yoowon¹⁴,Kim Hyeon Jeong¹⁴,Kim Siwon¹²,Kim Jushin¹⁴,Choi Ji Won¹,Kim Byungeun¹²,Lee Elijah Hwejin¹²,Kim Rium¹²,Seo Seon Hee¹,Lee Jaeick⁵^ORCID,Kim Jun Woo⁶,Lee Ha-Yeon⁶,Hwang Hayoung⁶,Bahn Yong-Sun⁴,Cheong Eunji⁴,Park Jong-Hyun¹²,Park Ki Duk¹²^ORCID

Affiliation:

1. Convergence Research Center for Diagnosis, Treatment & Care System of Dementia, Korea Institute of Science & Technology (KIST), Seoul 02792, Republic of Korea

2. Division of Bio-Med Science & Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Republic of Korea

3. Cureverse Co., Ltd., KIST, 1st Floor, H2 Building, Seoul 02792, Republic of Korea

4. Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea

5. Doping Control Center, KIST, Seoul 02792, Republic of Korea

6. New Drug Development Center, Daegu Gyeongbuk Medical Innovation Foundation (DGMIF), Daegu 41061, Republic of Korea

Funder

National Research Foundation of Korea

Korea Institute of Science and Technology

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01979

Reference42 articles.

1. MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice

2. Environmental Risk Factors for Multiple Sclerosis: A Review with a Focus on Molecular Mechanisms

3. T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

4. Sphingosine 1-phosphate in coagulation and inflammation

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