Global Analysis of Models for Predicting Human Absorption: QSAR, In Vitro, and Preclinical Models
Author:
Affiliation:
1. Research and Development, AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States
Funder
AbbVie Biotherapeutics
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00669
Reference103 articles.
1. Beyond the Rule of 5: Lessons Learned from AbbVie’s Drugs and Compound Collection
2. Why Some Targets Benefit from beyond Rule of Five Drugs
3. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
4. Two Decades under the Influence of the Rule of Five and the Changing Properties of Approved Oral Drugs
5. Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
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