Structure–Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors-Reference-Cited by-同舟云学术

Structure–Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors

Published:2022-02-24 Issue:5 Volume:65 Page:4335-4349
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Li Chunpu¹²³,Su Mingbo⁴,Zhu Wei¹,Kan Weijuan¹,Ge Tianpeng¹⁵,Xu Gaoya¹,Wang Shuni¹,Sheng Li¹,Gao Feng¹,Ye Yunfei⁶,Wang Jiang¹²,Zhou Yubo¹⁴⁷³,Li Jia¹⁴⁷²³,Liu Hong¹⁴²³^ORCID

Affiliation:

1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

2. School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, UCAS, Hangzhou 310024, China

3. University of Chinese Academy of Sciences, Beijing 100049, China

4. School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Qixia District, Nanjing 210023, China

5. College of Pharmacy, Weifang Medical University, Weifang 261053, China

6. School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China

7. Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan Tsuihang New District, Zhongshan, Guangdong 528400, China

Funder

Youth Innovation Promotion Association of the Chinese Academy of Sciences

National Natural Science Foundation of China

Lingang Laboratory

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c02156

Reference24 articles.

1. Advances toward LSD1 inhibitors for cancer therapy