Chiral Gd-DOTA as a Versatile Platform for Hepatobiliary and Tumor Targeting MRI Contrast Agents

Author:

Xu Weiyuan12,Ye Xinjian3,Wu Min4ORCID,Jiang Xin1,Hugo TSE Lik Hang5,Gu Yanjuan5,Shu Kun3,Xu Liuhui6,Jian Yong1,Mo Gengshen1,Xu Jiao1,Ding Yinghui1,Gao Ruonan1,Shen Jianliang1ORCID,Ye Fangfu162ORCID,Yan Zhihan3,Dai Lixiong167ORCID

Affiliation:

1. Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang 325000, China

2. Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang 325000, China

3. Department of Radiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China

4. Department of Radiology and Huaxi MR Research Center (HMRRC), Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

5. The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, Guangdong 518057, China

6. Joint Centre of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, China

7. Zhejiang Engineering Research Center for Innovation and Application of Intelligent Radiotherapy Technology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China

Funder

Wenzhou Municipal Science and Technology Bureau

University of Chinese Academy of Sciences

Anhui Laboratory of Molecule-Based Materials, Anhui Normal University

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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