Chiral Pyclen-Based Heptadentate Chelates as Highly Stable MRI Contrast Agents

Author:

Jian Yong12,Mo Gengshen2,Xu Weiyuan2,Liu Yao3,Zhang Zhichao2,Ding Yinghui2,Gao Ruonan2,Xu Jiao2,Zhu Jiang3ORCID,Shu Kun4,Yan Zhihan4,Carniato Fabio5ORCID,Platas-Iglesias Carlos6ORCID,Ye Fangfu12ORCID,Botta Mauro5ORCID,Dai Lixiong12ORCID

Affiliation:

1. Joint Centre of Translational Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China 325035

2. Joint Centre of Translational Medicine, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, People’s Republic of China 325000

3. Sichuan Key Laboratory of Medical Imaging, School of Pharmacy and Nanchong Key laboratory of MRI Contrast Agent, North Sichuan Medical College, Nanchong, People’s Republic of China 637000

4. Department of Radiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China 325027

5. Dipartimento di Scienze e Innovazione Tecnologica, Università del Piemonte Orientale, Viale T. Michel 11, Alessandria, Italy 15121

6. Departamento de Química Fundamental, Facultade de Ciencias, Universidade da Coruña, Campus da Zapateira-Rúa da Fraga 10, A Coruña, Spain 15008

Funder

Wenzhou Municipal Science and Technology Bureau

Anhui Laboratory of Molecule-Based Materials, Anhui Normal University

Wenzhou Institute of Biomaterials and Engineering

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

American Chemical Society (ACS)

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