F<scp>ragtory</scp>: Pharmacophore-Focused Design, Synthesis, and Evaluation of an sp<sup>3</sup>-Enriched Fragment Library-Reference-Cited by-同舟云学术

Fragtory: Pharmacophore-Focused Design, Synthesis, and Evaluation of an sp³-Enriched Fragment Library

Published:2023-05-02 Issue:9 Volume:66 Page:6297-6314
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bührmann Mike¹²,Kallepu Shivakrishna¹,Warmuth Jonas D.¹,Wiese Jan N.¹,Ehrt Christiane¹^ORCID,Vatheuer Helge¹,Hiller Wolf¹^ORCID,Seitz Carina³,Levy Laura²⁴,Czodrowski Paul¹,Sievers Sonja²³,Müller Matthias P.¹^ORCID,Rauh Daniel¹²^ORCID

Affiliation:

1. Department of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Strasse 4a, Dortmund 44227, Germany

2. Drug Discovery Hub Dortmund (DDHD) am Zentrum für integrierte Wirkstoffforschung (ZIW), Dortmund 44227, Germany

3. Max Planck Institute of Molecular Physiology, Compound Management and Screening Center (COMAS), Otto-Hahn-Strasse 11/15, Dortmund 44227, Germany

4. Taros Chemicals GmbH & Co. KG, Emil-Figge-Strasse 76a, Dortmund 44227, Germany

Funder

Bundesministerium f?r Bildung und Forschung

European Regional Development Fund

Deutsche Forschungsgemeinschaft

Ministerium f?r Kultur und Wissenschaft des Landes Nordrhein-Westfalen

Mercator Research Center Ruhr

Drug Discovery Hub Dortmund