DNA-encoded chemical libraries
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,General Biochemistry, Genetics and Molecular Biology
Link
https://www.nature.com/articles/s43586-021-00084-5.pdf
Reference116 articles.
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3. Melkko, S., Scheuermann, J., Dumelin, C. E. & Neri, D. Encoded self-assembling chemical libraries. Nat. Biotechnol. 22, 568–574 (2004).
4. Clark, M. A. et al. Design, synthesis and selection of DNA-encoded small-molecule libraries. Nat. Chem. Biol. 5, 647–654 (2009). First report of the synthesis of a numerically large DNA-encoded library using split-and-pool combinatorial chemistry and double-stranded DNA coding fragments.
5. Mannocci, L. et al. High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries. Proc. Natl Acad. Sci. USA 105, 17670–17675 (2008).
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