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Clearance in Drug Design

Published:2018-10-03 Issue:5 Volume:62 Page:2245-2255
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Smith Dennis A.¹,Beaumont Kevin²,Maurer Tristan S.²,Di Li³^ORCID

Affiliation:

1. 4 The Maltings, Walmer, Kent CT14 7AR, U.K.

2. Pharmacokinetics, Dynamics and Metabolism, Pfizer Inc., Cambridge, Massachusetts 02139, United States

3. Pharmacokinetics, Dynamics and Metabolism, Pfizer Inc., Groton, Connecticut 06340, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01263

Reference52 articles.

1. Pharmacokinetics and Metabolism in Drug Design

2. Drug Metabolism and Pharmacokinetics Quick Guide

3. Volume of Distribution in Drug Design

4. Relevance of Half-Life in Drug Design

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5. Optimization of Ethoxzolamide Analogs with Improved Pharmacokinetic Properties for In Vivo Efficacy against Neisseria gonorrhoeae;Journal of Medicinal Chemistry;2024-08-14

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