Discovery, synthesis and SAR of 2-acyl-1-biarylmethyl pyrazolidines, dual orexin receptor antagonists designed as fast and short-acting sleeping drugs
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Elsevier BV
Reference29 articles.
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2. Discovery of [(2R,5R)-5-[(5-fluoropyridin-2-yl)oxy]methyl-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): a dual orexin receptor antagonist with potent sleep-promoting properties;Coleman;ChemMedChem,2012
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5. Hcccighlights of prescribing information of Belsomra, Dayvigo and Quviviq can be downloaded from the followings URLs respectively: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/204569s006lbl.pdf; https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/212028s000lbl.pdf; https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/214985s000lbl.pdf.
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