Contilisant, a Tetratarget Small Molecule for Alzheimer’s Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile-Reference-Cited by-同舟云学术

Contilisant, a Tetratarget Small Molecule for Alzheimer’s Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile

Published:2018-07-03 Issue:15 Volume:61 Page:6937-6943
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bautista-Aguilera Óscar M.¹,Budni Josiane²,Mina Francielle²,Medeiros Eduarda Behenck²,Deuther-Conrad Winnie³,Entrena José M.⁴,Moraleda Ignacio⁵,Iriepa Isabel⁵,López-Muñoz Francisco⁶⁷,Marco-Contelles José¹^ORCID

Affiliation:

1. Laboratory of Medicinal Chemistry, IQOG, CSIC, C/Juan de la Cierva 3, 28006 Madrid, Spain

2. Laboratório de Neurologia Experimental, Universidade do Extremo Sul Catarinense, Av. Universitária, 1105 Criciúma, Brazil

3. Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 04318 Leipzig, Germany

4. Animal Behavior Research Unit, Scientific Instrumentation Center, University of Granada, Parque Tecnológico de Ciencias de la Salud, 18100 Armilla, Granada, Spain

5. Departamento de Química Orgánica and Química Inorgánica, Universidad de Alcalá, Ctra. Madrid-Barcelona, Km. 33,6, 28871 Madrid, Spain

6. Faculty of Health, Camilo José Cela University, 28692 Villanueva de la Cañada, Madrid, Spain

7. Neuropsychopharmacology Unit, “Hospital 12 de Octubre” Research Institute, 28041 Madrid, Spain

Funder

Ministerio de Econom?a y Competitividad

European Union Agency for Network and Information Security

UCJC

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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