Synthesis and Antiviral Evaluation of Carbocyclic Nucleoside Analogs of Nucleoside Reverse Transcriptase Translocation Inhibitor MK-8591 (4′-Ethynyl-2-fluoro-2′-deoxyadenosine)-Reference-Cited by-同舟云学术

Synthesis and Antiviral Evaluation of Carbocyclic Nucleoside Analogs of Nucleoside Reverse Transcriptase Translocation Inhibitor MK-8591 (4′-Ethynyl-2-fluoro-2′-deoxyadenosine)

Published:2018-09-28 Issue:20 Volume:61 Page:9218-9228
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Alexandre François-René¹^ORCID,Rahali Rachid¹,Rahali Houcine¹,Guillon Sandra²,Convard Thierry¹,Fillgrove Kerry³,Lai Ming-Tain³,Meillon Jean-Christophe²,Xu Min³,Small James³,Dousson Cyril B.¹,Raheem Izzat T.³^ORCID

Affiliation:

1. Idenix an MSD Company, Cap Gamma, 1682 Rue de la Valsière, 34189 Montpellier Cedex 4, France

2. Oxeltis, Cap Delta, 1682 Rue de la Valsière, 34189 Montpellier Cedex 4, France

3. Merck & Co., Inc., P.O. Box 4, 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00141

Reference39 articles.

1. The Nucleoside Reverse Transcriptase Inhibitors, Nonnucleoside Reverse Transcriptase Inhibitors, and Protease Inhibitors in the Treatment of HIV Infections (AIDS)

2. A 40-Year Journey in Search of Selective Antiviral Chemotherapy*

3. 10.4172/jaa.1000036

4. NRTI Backbone in HIV Treatment

5. Development and optimization of anti-HIV nucleoside analogs and prodrugs:

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