Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19-Reference-Cited by-同舟云学术

Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19

Published:2020-10-15 Issue:21 Volume:63 Page:12725-12747
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hoffman Robert L.¹^ORCID,Kania Robert S.¹,Brothers Mary A.¹,Davies Jay F.¹,Ferre Rose A.¹,Gajiwala Ketan S.¹,He Mingying¹,Hogan Robert J.²,Kozminski Kirk¹,Li Lilian Y.¹,Lockner Jonathan W.¹^ORCID,Lou Jihong¹,Marra Michelle T.¹,Mitchell Lennert J.¹,Murray Brion W.¹,Nieman James A.¹^ORCID,Noell Stephen¹,Planken Simon P.¹^ORCID,Rowe Thomas²,Ryan Kevin¹,Smith George J.¹,Solowiej James E.¹,Steppan Claire M.¹,Taggart Barbara²

Affiliation:

1. Pfizer Worldwide Research and Development, 10770 Science Center Drive, San Diego, California 92121 United States

2. Southern Research Institute, 2000 9th Avenue South, Birmingham, Alabama 35205 United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01063

Reference51 articles.

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