Automated Design of Macrocycles for Therapeutic Applications: From Small Molecules to Peptides and Proteins-Reference-Cited by-同舟云学术

Automated Design of Macrocycles for Therapeutic Applications: From Small Molecules to Peptides and Proteins

Published:2020-10-05 Issue:20 Volume:63 Page:12100-12115
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sindhikara Dan¹,Wagner Michael²,Gkeka Paraskevi³^ORCID,Güssregen Stefan²^ORCID,Tiwari Garima²,Hessler Gerhard²,Yapici Engin¹,Li Ziyu²,Evers Andreas²^ORCID

Affiliation:

1. Schrodinger, Inc., 120 West 45th Street, New York, New York 10036, United States

2. Integrated Drug Discovery, Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, 65926 Frankfurt am Main, Germany

3. Integrated Drug Discovery, Sanofi R&D, 1 Avenue Pierre Brossolette, 91385 Chilly-Mazarin, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01500

Reference151 articles.

1. Macrocycles as protein–protein interaction inhibitors

2. Macrocycles: lessons from the distant past, recent developments, and future directions

3. Recent advances in the synthesis of cyclic pseudopeptides

4. Protein-protein interaction modulators: advances, successes and remaining challenges

5. Natural Cyclic Peptides as an Attractive Modality for Therapeutics: A Mini Review

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