Identification of Micrococcin P2-Derivatives as Antibiotic Candidates against Two Gram-Positive Pathogens

Author:

Kim Dahyun1,Lee Jusuk1,Shyaka Clovis1,Kwak Jin-Hwan23,Pai Hyunjoo4,Rho Mina5,Ciufolini Marco A.6,Han Minwoo7ORCID,Park Jong-Hwan89,Kim Young-Rok2,Jung Sungji2,Jang Ah-Ra9,Kim Eunjung2,Lee Jee-Young7,Lee Hakyeong1,Son Young-Jin1ORCID,Hwang Hee-Jong1ORCID

Affiliation:

1. A&J Science Co., Ltd., 80 Chumbok Ro, Dong Gu, Daegu 41061, Republic of Korea

2. School of Life Science, Handong Global University, 558 Handong Ro, Heunghae-Eup, Buk-Gu, Pohang 37554, Republic of Korea

3. Office of the President, Sunlin University, 30, 36 Chogok-gil, Heunghae-Eup, Buk-Gu, Pohang 37560, Republic of Korea

4. Department of Internal Medicine, Hanyang University College of Medicine, 232 Wangsimri Ro, Seongdong-Gu, Seoul 04763, Republic of Korea

5. Department of Computer Science, Hanyang University, 222 Wangsimri Ro, Seongdong-Gu, Seoul 04763, Republic of Korea

6. Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6K 1Z1, Canada

7. New Drug Development Center, Daegu Gyeongbuk Medical Innovation Foundation, 80 Chumbok Ro, Dong Gu, Daegu 41061, Republic of Korea

8. Laboratory Animal Medicine, College of Veterinary Medicine and Animal Medical Institute, Chonnam National University, 77 Yongbong-ro, Buk-Gu, Gwangju 61186, Republic of Korea

9. Nodcure Inc., 77 Yongbong-ro, Buk-Gu, Gwangju 61186, Republic of Korea

Funder

Korea Health Industry Development Institute

Circle Foundation

A&J Science Co.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference68 articles.

1. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

2. The global preclinical antibacterial pipeline

3. Centers for Disease Control and Prevention (CDC). Antibiotic/antimicrobial resistance (AR/AMR), biggest threats and data. https://www.cdc.gov/drugresistance/biggest_threats.html (accessed April 27, 2023).

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