Identification of Novel GPR55 Modulators Using Cell-Impedance-Based Label-Free Technology-Reference-Cited by-同舟云学术

Identification of Novel GPR55 Modulators Using Cell-Impedance-Based Label-Free Technology

Published:2016-02-05 Issue:5 Volume:59 Page:1840-1853
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Morales Paula¹,Whyte Lauren S.²,Chicharro Roberto¹,Gómez-Cañas María³⁴⁵,Pazos M. Ruth³⁴⁵,Goya Pilar¹,Irving Andrew J.⁶,Fernández-Ruiz Javier³⁴⁵,Ross Ruth A.²,Jagerovic Nadine¹

Affiliation:

1. Instituto de Química Médica, CSIC, Calle Juan de la Cierva, 3, 28006 Madrid, Spain

2. Department of Pharmacology and Toxicology, Medical Sciences Building, University of Toronto, 1 King’s College Circle, Toronto, Ontario M5S 1A8, Canada

3. Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain

4. Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 28040 Madrid, Spain

5. Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), 28034 Madrid, Spain

6. School of Biomolecular and Biomedical Science, University College Dublin, Dublin D4, Ireland

Funder

University of Toronto

Consejo Superior de Investigaciones Cient?ficas

Ministerio de Econom?a y Competitividad

European Social Fund

Comunidad de Madrid

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01331

Reference61 articles.

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3. Brown, A. J.; Wise, A.(Glaxosmithkline) Identification of modulators of GPR55 activity, WO2001/86305A2, 2001.

4. GPR55 and GPR35 and their relationship to cannabinoid and lysophospholipid receptors

5. The therapeutic potential of orphan GPCRs, GPR35 and GPR55

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