Thienopyrimidine Derivatives as GPR55 Receptor Antagonists: Insight into Structure–Activity Relationship-Reference-Cited by-同舟云学术

Thienopyrimidine Derivatives as GPR55 Receptor Antagonists: Insight into Structure–Activity Relationship

Published:2022-12-02 Issue:1 Volume:14 Page:18-25
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Figuerola-Asencio Laura¹,Morales Paula¹^ORCID,Zhao Pingwei²,Hurst Dow P.³,Sayed Sommayah S.³,Colón Katsuya L.³,Gómez-Cañas María⁴,Fernández-Ruiz Javier⁴^ORCID,Croatt Mitchell P.³^ORCID,Reggio Patricia H.³,Abood Mary E.²,Jagerovic Nadine¹^ORCID

Affiliation:

1. Instituto de Química Médica, Consejo Superior de Investigaciones Científicas, 28006Madrid, Spain

2. Center for Substance Abuse Research, Temple University, Philadelphia, Pennsylvania19122, United States

3. Center for Drug Discovery, Department of Chemistry and Biochemistry, University North Carolina, Greensboro, North Carolina27599, United States

4. Department of Biochemistry and Molecular Biology, Faculty of Medicine, Complutense University, CIBERNED and IRYCIS, 28040Madrid, Spain

Funder

Consejo Superior de Investigaciones Cient?ficas

Comunidad de Madrid

Ministerio de Ciencia, Innovaci?n y Universidades

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.2c00325

Reference35 articles.

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2. Identification and cloning of three novel human G protein-coupled receptor genes GPR52, ΨGPR53 and GPR55: GPR55 is extensively expressed in human brain

3. Wise, A.; Brown, A. J.Identification of Modulators of GPR55. WO200186305, 2001.

4. Drmota, T.; Greasley, P.; Groblewski, T.; Drmota, P.; Greasley, P.; Groblewski, T.Screening Assays for Cannabinoid- Ligand Type Modulators. WO2004074844, 2004.