C7β-Methyl Analogues of the Orvinols: The Discovery of Kappa Opioid Antagonists with Nociceptin/Orphanin FQ Peptide (NOP) Receptor Partial Agonism and Low, or Zero, Efficacy at Mu Opioid Receptors
Author:
Affiliation:
1. Department of Pharmacy and Pharmacology, University of Bath, Bath, BA2 7AY, United Kingdom
2. Department of Pharmacology, University of Michigan, Ann Arbor, Michigan 48109, United States
Funder
National Institute on Drug Abuse
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00130
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