Opioid Antagonists from the Orvinol Series as Potential Reversal Agents for Opioid Overdose-Reference-Cited by-同舟云学术

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Opioid Antagonists from the Orvinol Series as Potential Reversal Agents for Opioid Overdose

Published:2022-10-12 Issue:21 Volume:13 Page:3108-3117
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Disney Alex¹,Olson Keith M.²,Shafer Amanda M.²,Moore Sierra C.²,Anand Jessica P.²,Traynor John R.²³,Husbands Stephen M.¹^ORCID

Affiliation:

1. Medicinal Chemistry Section, Department of Life Sciences, University of Bath, Bath BA2 7AY, U.K.

2. Department of Pharmacology and Edward F Domino Research Center, University of Michigan, Ann Arbor, Michigan 48109 United States

3. Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan 48109 United States

Funder

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.2c00464

Reference21 articles.

1. Centers for Disease Control and Prevention. https://www.cdc.gov/drugoverdose/data/fentanyl.html (accessed July, 2020).

2. Fentanyl depression of respiration: Comparison with heroin and morphine

3. Naloxone for heroin, prescription opioid, and illicitly made fentanyl overdoses: Challenges and innovations responding to a dynamic epidemic

4. Characteristics of Fentanyl Overdose — Massachusetts, 2014–2016

5. The Orvinols and Related Opioids - High Affinity Ligands with Diverse Efficacy Profiles

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1. Machine Learned Classification of Ligand Intrinsic Activities at Human μ-Opioid Receptor;ACS Chemical Neuroscience;2024-07-11

2. Machine Learned Classification of Ligand Intrinsic Activities at Humanµ-Opioid Receptor;2024-04-10

3. IUPHAR review: Recent progress in the development of Mu opioid receptor modulators to treat opioid use disorders;Pharmacological Research;2024-01

4. Endogenous opiates and behavior: 2022;Peptides;2023-11

5. Opioid Overdose: Limitations in Naloxone Reversal of Respiratory Depression and Prevention of Cardiac Arrest;Anesthesiology;2023-07-04

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