Identification of Substituted Naphthotriazolediones as Novel Tryptophan 2,3-Dioxygenase (TDO) Inhibitors through Structure-Based Virtual Screening-Reference-Cited by-同舟云学术

Identification of Substituted Naphthotriazolediones as Novel Tryptophan 2,3-Dioxygenase (TDO) Inhibitors through Structure-Based Virtual Screening

Published:2015-09-16 Issue:19 Volume:58 Page:7807-7819
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wu Jian-Sung¹,Lin Shu-Yu¹,Liao Fang-Yu¹,Hsiao Wen-Chi¹,Lee Lung-Chun¹,Peng Yi-Hui¹,Hsieh Chia-Ling¹,Wu Mine-Hsine¹,Song Jen-Shin¹,Yueh Andrew¹,Chen Chun-Hwa¹,Yeh Shiu-Hwa¹,Liu Chia-Yeh²,Lin Shu-Yi²,Yeh Teng-Kuang¹,Hsu John T.-A.¹,Shih Chuan¹,Ueng Shau-Hua¹,Hung Ming-Shiu¹,Wu Su-Ying¹

Affiliation:

1. Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350, Taiwan, ROC

2. Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350, Taiwan, ROC

Funder

National Health Research Institutes

National Science Council Taiwan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00921

Reference55 articles.

1. Exploring the mechanism of tryptophan 2,3-dioxygenase

2. Kynurenines in the mammalian brain: when physiology meets pathology