Effect of Chirality on Common in Vitro Experiments: An Enantiomeric Pair Analysis-Reference-Cited by-同舟云学术

Effect of Chirality on Common in Vitro Experiments: An Enantiomeric Pair Analysis

Published:2015-08-04 Issue:15 Volume:58 Page:5781-5788
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bagdanoff Jeffrey T.¹,Xu Yongjin²,Dollinger Gavin²,Martin Eric²

Affiliation:

1. Global Discovery Chemistry/Oncology and Exploratory Chemistry, Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States

2. Global Discovery Chemistry/Oncology and Exploratory Chemistry, Novartis Institutes for BioMedical Research, 4560 Horton Street, Building 4, Emeryville, California 94608, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00552

Reference54 articles.

1. IAM chromatography: an in vitro screen for predicting drug membrane permeability

2. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

3. Drug-like properties and the causes of poor solubility and poor permeability

4. Drugs, leads, and drug-likeness: an analysis of some recently launched drugs

5. A Comparison of Physiochemical Property Profiles of Development and Marketed Oral Drugs

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Thianthrenation-Enabled Pyrrolidin-2-yl and Tetrahydrofuran-2-yl Methylation of (Hetero)Arenes;Organic Letters;2023-04-11

2. Hearing loss drug discovery and medicinal chemistry: Current status, challenges, and opportunities;Progress in Medicinal Chemistry;2022

3. Discovery of Acyl-sulfonamide Nav1.7 Inhibitors GDC-0276 and GDC-0310;Journal of Medicinal Chemistry;2021-03-08

4. Racemisation in Chemistry and Biology;Chemistry – A European Journal;2020-03-23

5. The problem of racemization in drug discovery and tools to predict it;Expert Opinion on Drug Discovery;2019-03-18