Silmitasertib (CX-4945), a Clinically Used CK2-Kinase Inhibitor with Additional Effects on GSK3β and DYRK1A Kinases: A Structural Perspective-Reference-Cited by-同舟云学术

Silmitasertib (CX-4945), a Clinically Used CK2-Kinase Inhibitor with Additional Effects on GSK3β and DYRK1A Kinases: A Structural Perspective

Published:2023-03-08 Issue:6 Volume:66 Page:4009-4024
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Grygier Przemyslaw¹^ORCID,Pustelny Katarzyna¹^ORCID,Nowak Jakub¹,Golik Przemyslaw²,Popowicz Grzegorz M.³⁴,Plettenburg Oliver⁵⁶⁷⁸,Dubin Grzegorz¹^ORCID,Menezes Filipe³⁴^ORCID,Czarna Anna¹

Affiliation:

1. Malopolska Centre of Biotechnology, Jagiellonian University, Gronostajowa 7A, 30-387 Krakow, Poland

2. Selvita S.A, Bobrzynskiego, 14, 30-338 Krakow, Poland

3. Institute of Structural Biology, Helmholtz Zentrum Muenchen, Ingolstaedter Landstrasse 1, Neuherberg 85764, Germany

4. Biomolecular NMR and Center for Integrated Protein Science Munich at Department Chemie, Technical University of Munich, Lichtenbergstrasse 4, Garching 85747, Germany

5. Institute of Medicinal Chemistry, Helmholtz Munich, Ingolstaedter Landstrasse 1, Neuherberg 85764, Germany

6. Institute of Organic Chemistry, Centre of Biomolecular Drug Research (BMWZ) and Laboratory of Nano and Quantum Engineering (LNQE), Leibniz University Hannover, Schneiderberg 1b, Hannover 30167, Germany

7. German Center for Diabetes Research (DZD), Ingolstaedter Landstrasse 1, Neuherberg 85764, Germany

8. Institute of Lung Health (ILH), Aulweg 130, Giessen 35392, Germany

Funder

Narodowa Agencja Wymiany Akademickiej

Narodowe Centrum Nauki

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01887

Reference85 articles.