Kinase mutations in human disease: interpreting genotype–phenotype relationships-Reference-Cited by-同舟云学术

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Kinase mutations in human disease: interpreting genotype–phenotype relationships

Published:2010-01 Issue:1 Volume:11 Page:60-74
ISSN:1471-0056
Container-title:Nature Reviews Genetics
language:en
Short-container-title:Nat Rev Genet

Author:

Lahiry Piya,Torkamani Ali,Schork Nicholas J.,Hegele Robert A.

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Genetics,Molecular Biology

Link

http://www.nature.com/articles/nrg2707.pdf

Reference120 articles.

1. Manning, G., Whyte, D. B., Martinez, R., Hunter, T. & Sudarsanam, S. The protein kinase complement of the human genome. Science 298, 1912–1934 (2002). This landmark article established the size, range and implications of the protein kinase family in the human genome.

2. Hubbard, M. J. & Cohen, P. On target with a new mechanism for the regulation of protein phosphorylation. Trends Biochem. Sci. 18, 172–177 (1993).

3. Hopkins, A. L. & Groom, C. R. The druggable genome. Nature Rev. Drug Discov. 1, 727–730 (2002).

4. Torkamani, A. & Schork, N. J. Distribution analysis of nonsynonymous polymorphisms within the human kinase gene family. Genomics 90, 49–58 (2007).

5. Hanks, S. K. & Hunter, T. Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J. 9, 576–596 (1995).

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