Exploring Novel GSK-3β Inhibitors for Anti-Neuroinflammatory and Neuroprotective Effects: Synthesis, Crystallography, Computational Analysis, and Biological Evaluation-Reference-Cited by-同舟云学术

Exploring Novel GSK-3β Inhibitors for Anti-Neuroinflammatory and Neuroprotective Effects: Synthesis, Crystallography, Computational Analysis, and Biological Evaluation

Published:2024-08-19 Issue:17 Volume:15 Page:3181-3201
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Góral Izabella¹²,Wichur Tomasz¹,Sługocka Emilia¹²³,Grygier Przemysław³⁴^ORCID,Głuch-Lutwin Monika⁵,Mordyl Barbara⁵,Honkisz-Orzechowska Ewelina⁶,Szałaj Natalia¹,Godyń Justyna¹^ORCID,Panek Dawid¹,Zaręba Paula¹^ORCID,Sarka Anna⁶,Żmudzki Paweł⁷,Latacz Gniewomir⁶,Pustelny Katarzyna⁸^ORCID,Bucki Adam⁷^ORCID,Czarna Anna³,Menezes Filipe⁹,Więckowska Anna¹^ORCID

Affiliation:

1. Department of Physicochemical Drug Analysis, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna St., Krakow 30-688, Poland

2. Doctoral School of Medical and Health Sciences, Jagiellonian University Medical College, 16 Lazarza St., Krakow 31-530, Poland

3. Malopolska Centre of Biotechnology, Jagiellonian University, Gronostajowa 7a, Krakow 30-387, Poland

4. Doctoral School of Exact and Natural Sciences, Jagiellonian University, Lojasiewicza 11, Krakow 30-348, Poland

5. Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna St., Krakow 30-688, Poland

6. Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna St., Krakow 30-688, Poland

7. Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna St., Krakow 30-688, Poland

8. Department of Physical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7 St., Krakow 30-387, Poland

9. Helmholtz Munich, Molecular Targets and Therapeutics Center, Institute of Structural Biology, Ingolstädter Landstr. 1, Neuherberg 85764, Germany

Funder

Uniwersytet Jagiellonski Collegium Medicum

Narodowe Centrum Nauki

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.4c00365

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