Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening
Author:
Affiliation:
1. Center for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, New Jersey 08854, United States
2. Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, United States
Funder
National Institute of Allergy and Infectious Diseases
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01681
Reference69 articles.
1. Advantages of crystallographic fragment screening: Functional and mechanistic insights from a powerful platform for efficient drug discovery
2. Tethering: Fragment-Based Drug Discovery
3. A decade of fragment-based drug design: strategic advances and lessons learned
4. Fragment-based activity space: smaller is better
5. Ligand efficiency and fragment-based drug discovery
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