Advantages of crystallographic fragment screening: Functional and mechanistic insights from a powerful platform for efficient drug discovery-Reference-Cited by-同舟云学术

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Advantages of crystallographic fragment screening: Functional and mechanistic insights from a powerful platform for efficient drug discovery

Published:2014-11 Issue:2-3 Volume:116 Page:92-100
ISSN:0079-6107
Container-title:Progress in Biophysics and Molecular Biology
language:en
Short-container-title:Progress in Biophysics and Molecular Biology

Author:

Patel Disha,Bauman Joseph D.,Arnold Eddy

Funder

NSF

NIH/NIGMS

NIH/NCRR

U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences

Publisher

Elsevier BV

Subject

Molecular Biology,Biophysics

Reference44 articles.

1. PHENIX: a comprehensive python-based system for macromolecular structure solution;Adams;Acta Crystallogr. Sect. D. Biol. Crystallogr.,2010

2. An experimental approach to mapping the binding surfaces of crystalline proteins;Allen;J. Phys. Chem.,1996

3. Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant;Atwell;Protein Eng. Des. Sel.,2010

4. Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design;Bauman;Nucleic Acids Res.,2008

5. Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors;Bauman;ACS Chem. Biol.,2013

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