A decade of fragment-based drug design: strategic advances and lessons learned
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd2220.pdf
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3. Hardy, L. W. & Peet, N. P. The multiple orthogonal tools approach to define molecular causation in the validation of druggable targets. Drug Discov. Today 9, 117–126 (2004).
4. Betz, U. A., Farquhar, R. & Ziegelbauer, K. Genomics: success or failure to deliver drug targets? Curr. Opin. Chem. Biol. 9, 387–391 (2005).
5. Zambrowicz, B. P. & Sands, A. T. Knockouts model the 100 best-selling drugs — will they model the next 100? Nature Rev. Drug Discov. 2, 38–51 (2003).
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