Synthesis and Discovery of High Affinity Folate Receptor-Specific Glycinamide Ribonucleotide Formyltransferase Inhibitors with Antitumor Activity-Reference-Cited by-同舟云学术

Synthesis and Discovery of High Affinity Folate Receptor-Specific Glycinamide Ribonucleotide Formyltransferase Inhibitors with Antitumor Activity

Published:2008-08-01 Issue:16 Volume:51 Page:5052-5063
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Deng Yijun¹,Wang Yiqiang¹,Cherian Christina¹,Hou Zhanjun¹,Buck Steven A.¹,Matherly Larry H.¹,Gangjee Aleem¹

Affiliation:

1. Graduate Program in Cancer Biology, Wayne State University School of Medicine, Detroit, Michigan 48201, Division of Medicinal Chemistry, Graduate School Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282, Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan 48201, Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Detroit, Michigan 48201, and Department of Pediatrics, Children’s Hospital of Michigan, Detroit, Michigan...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8003366

Reference39 articles.

1. Membrane Transport of Folates

2. Human reduced folate carrier: translation of basic biology to cancer etiology and therapy

3. Resistance to antifolates

4. Identification of an Intestinal Folate Transporter and the Molecular Basis for Hereditary Folate Malabsorption

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