Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria-Reference-Cited by-同舟云学术

Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria

Published:2023-08-15 Issue:16 Volume:66 Page:11294-11323
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Nayeen Md. Junayed¹,Katinas Jade M.²,Magdum Tejashree¹^ORCID,Shah Khushbu¹,Wong Jennifer E.²,O’Connor Carrie E.³,Fifer Alexandra N.²,Wallace-Povirk Adrianne³^ORCID,Hou Zhanjun³⁴^ORCID,Matherly Larry H.³⁴^ORCID,Dann Charles E.²,Gangjee Aleem¹^ORCID

Affiliation:

1. Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282, United States

2. Department of Chemistry, Indiana University, Bloomington, Indiana 47408, United States

3. Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan 48201, United States

4. Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, 4100 John R, Detroit, Michigan 48201, United States

Funder

National Cancer Institute

Wayne State University

National Institute of General Medical Sciences

Duquesne University

Publisher

American Chemical Society (ACS)