Structural Characterization of 5-Substituted Pyrrolo[3,2-<i>d</i>]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2-Reference-Cited by-同舟云学术

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Structural Characterization of 5-Substituted Pyrrolo[3,2-d]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2

Published:2024-02-07 Issue: Volume: Page:
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Katinas Jade M.¹,Nayeen Md. Junayed²,Schneider Mathew³,Shah Khushbu²,Fifer Alexandra N.¹,Klapper Lily M.¹,Sharma Abhishekh²,Thalluri Kishore¹,Van Nieuwenhze Michael S.¹,Hou Zhanjun³^ORCID,Gangjee Aleem²^ORCID,Matherly Larry H.³^ORCID,Dann Charles E.¹^ORCID

Affiliation:

1. Department of Chemistry, Indiana University, Bloomington, Indiana 47405, United States

2. School of Pharmacy & Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282, United States

3. Barbara Ann Karmanos Cancer Institute, Department of Oncology, Wayne State University, 4100 John R, Detroit, Michigan 48201, United States

Funder

National Cancer Institute

Duquesne University

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.3c00613

Reference50 articles.

1. One-Carbon Metabolism in Health and Disease

2. One-carbon metabolism in cancer

3. Serine and one-carbon metabolism in cancer

4. Beyond the Warburg Effect: How Do Cancer Cells Regulate One-Carbon Metabolism?

5. Mechanisms of Membrane Transport of Folates into Cells and Across Epithelia

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Structural insights into binding of polyglutamylated tetrahydrofolate by serine hydroxymethyltransferase 8 from soybean;Frontiers in Plant Science;2024-08-19

2. Universality of critical active site glutamate as an acid–base catalyst in serine hydroxymethyltransferase function;Chemical Science;2024

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