Tethering Small Molecules to a Phage Display Library: Discovery of a Selective Bivalent Inhibitor of Protein Kinase A
Author:
Affiliation:
1. Department of Chemistry, University of Arizona, Tucson, Arizona 85721
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja076197d
Reference25 articles.
1. Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy
2. Fragment-Based Drug Discovery
3. Rapid Access to Unexplored Chemical Space by Ligand Scanning around a Ruthenium Center: Discovery of Potent and Selective Protein Kinase Inhibitors
4. A decade of fragment-based drug design: strategic advances and lessons learned
5. The Protein Kinase Complement of the Human Genome
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