Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy-Reference-Cited by-同舟云学术

Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy

Published:2003-03-12 Issue:14 Volume:125 Page:4087-4096
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Szczepankiewicz Bruce G.¹,Liu Gang¹,Hajduk Philip J.¹,Abad-Zapatero Cele¹,Pei Zhonghua¹,Xin Zhili¹,Lubben Thomas H.¹,Trevillyan James M.¹,Stashko Michael A.¹,Ballaron Stephen J.¹,Liang Heng¹,Huang Flora¹,Hutchins Charles W.¹,Fesik Stephen W.¹,Jirousek Michael R.¹

Affiliation:

1. Contribution from the Global Pharmaceutical Research and Development Organization, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja0296733

Reference46 articles.

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2. The regulation of protein function by multisite phosphorylation – a 25 year update

3. Introduction: Protein Phosphorylation and Signaling

4. Synthesis of 4-(Phenylamino)pyrimidine Derivatives as ATP-Competitive Protein Kinase Inhibitors with Potential for Cancer Chemotherapy

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